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Diffusion Cells

LabECX provides Franz Cells, Horizontal Cells like the Crown Glass Side-Bi-Side cells, and related equipment for studying membrane transport and drug diffusion through biological and synthetic membranes. Applications include experimentation in the areas of drug discovery, drug transport, drug screening, controlled release, formulation optimization, dermatology, skin toxicology, oral absorption, buccal absorption, percutaneous absorption, equilibrium dialysis and protein binding.

The most popular application is in the development of transdermal and topical pharmaceuticals. However, our equipment is also used in basic research or preformulation projects requiring measurement of diffusion coefficients, partition coefficients, and membrane permeabilities.

We provide both specialized diffusion cells for research projects, such as iontophoresis, and automatic sampling systems for high-output measurements, such as in vitro release from topical pharmaceuticals.

Horizontal Cell or Side-Bi-Side Cell

We have previously provided Bronaugh Cells, Drive Consoles, and other apparatus for Crown Glass Company and Crown BioScientific until 1994. We still manufacture some of those products as well as our own innovative diffusion equipment like the In-Line Cell. We now blow our own glass cells which are identical to the classic Franz cell and Crown Glass Side-Bi-Side cell.

The technological advances in microprocessors and software are making it increasingly more feasible for companies to improve productivity through automation. Project managers face a risk, however, recommending large expenditures now without guarantee of positive returns in the future. Furthermore, we believe that highly trained individuals should not be diverted from their primary research and development projects.

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